Fast acting night time relief for aches and pains.

Key benefits of Panadol Night:

• Relieves pain and can reduce fever
• Fast and effective
• Relieves night time pain
• Tablet form

Panadol NightPain tablets provide fast and effective relief of bed time pain including headaches, backache, rheumatic pains and muscle pains, period pains and toothache which is causing difficulty in getting to sleep.

Panadol Night tablets have two active ingredients. Paracetamol relieves pain and can reduce fever. Diphenhydramine hydrochloride is an antihistamine which causes sleepiness. This ingredient makes you feel drowsy or sleepy, helping you to fall asleep when you find that your pain is keeping you awake at night.

Panadol Night should only be taken at bedtime.

Each tablet contains Paracetamol 500 mg and Diphenhydramine Hydrochloride 25 mg.

Active ingredients:

Each tablet contains Paracetamol 500 mg and Diphenhydramine Hydrochloride 25 mg.

Other ingredients:

Maize starch, starch pre-gelatinised, potassium sorbate (E 202), povidone, purified talc, stearic acid, hypromellose (E 464), titanium dioxide (E 171), lactose monohydrate, macrogol 400, triacetin, brilliant blue FCF (E 133), indigo carmine (E 132) and carnauba wax.

Adults 16+ take 2 tablets about 20 minutes before bedtime.

Do not take more than 2 tablets per night.

Do not take Panadol Night for more than 7 consecutive nights without consulting your doctor.

Adults (including the elderly) and children aged 16 years and over:

Two tablets to be taken 20 minutes before bedtime. Maximum daily dose: Two tablets (1000 mg paracetamol, 50 mg diphenhydramine hydrochloride) in 24 hours.

Other products containing paracetamol may be taken for daytime pain relief but at a reduced maximum dose of 6 tablets in 24 hours. The dose should not be repeated more frequently than every four hours.

Should not be used with other antihistamine-containing preparations, including those used on the skin

The lowest dose necessary to achieve efficacy should be used for the shortest duration of treatment.

Not recommended for children under 16 years of age except on medical advice.

Patients should not take the tablets for more than 7 consecutive nights without consulting their doctor.

Elderly: Should not be taken by elderly patients with confusion. Sedating antihistamines may cause confusion and paradoxical excitation in the elderly

Caution should be exercised in those with moderate to severe hepatic or renal impairment.

Not recommended for children under 16 years of age except on medical advice.

Patients should not take the tablets for more than 7 consecutive nights without consulting their doctor.

Elderly: Should not be taken by elderly patients with confusion. Sedating antihistamines may cause confusion and paradoxical excitation in the elderly

Caution should be exercised in those with moderate to severe hepatic or renal impairment.

Avoid use of other antihistamine-containing preparations, including topical antihistamine and cough and cold medicines.

Avoid concurrent use with alcohol, as diphenhydramine may increase the sedative effects of alcohol. Therefore, alcohol should be avoided (see Interactions).

Medical advice should be sought before taking in patients with:

• Hepatic or renal impairment. Underlying liver disease increases the risk of paracetamol-related liver damage
• Glutathione depleted states as the use of paracetamol may increase the risk of metabolic acidosis
• Concurrent use of drugs which cause sedation such as tranquillizers, hypnotics and anxiolytics as diphenhydramine may cause an increase in sedative effects (see interactions).

Use with caution in:

• Patients with epilepsy or seizure disorders, myasthenia gravis, narrow-angle glaucoma, prostatic hypertrophy, urinary retention, asthma, bronchitis and chronic obstructive pulmonary disease (COPD), hepatic impairment and mild to moderate renal impairment.
• Patients taking monoamine oxidase inhibitors (MAOIs) or within 2 weeks of stopping an MAOI (see Interactions).
• Patients taking other drugs with antimuscarinic properties (e.g. atropine, tricyclic antidepressants (see Interactions).