Cardio on Foundayo: What Walkers, Class-Goers and Gym Regulars Report

Foundayo (orforglipron) is a once-daily tablet licensed in the UK for weight management as an adjunct to a reduced-calorie diet and increased physical activity. For people taking it, "increased physical activity" quickly becomes a practical question: will the treadmill, the class or the evening walk feel the same once appetite and energy start to shift?

These are personal accounts from public forums, mostly American. They cannot show how often anything happens or why, and they differ a great deal. Some people describe cardio that carries on untouched, others a flat patch in the first weeks, and many a gradual rebuilding of what they can do.


Business as Usual

For a number of people, the surprise is how little changes. One person who kept exercising through the first fortnight reports no obstacle at all.

"I haven’t had many side effects at all- especially not one that would hinder my ability to work out. I’m only two weeks in but I’ve been working out 4-5 times a week with zero issue. Oddly more energy and feeling better than before I started."
– Admarie25

Nor is that limited to gentle sessions. A man who started training again at the same time as the tablets describes a weekly schedule that is anything but easy.

"I began working out again at the same time. 4 days per week of moderate to intense cardio; two days of strength and one day of rest."
– lookmanolurker

Intensity can be quite precise when people are tracking it, as in this account from a woman in her fifties who teaches group fitness.

"I exercise 3-5 times a week (really sweating and getting my heartbeat up over 125 bpm for 30 mins or more) as well as walking every day and getting good sleep."
– Consistent-Slice-840

Not every routine survives unscathed, though, and the exceptions tend to cluster around the first weeks and the days after a dose changes.


The Flat Patch

Tiredness is the complaint that most often collides with exercise, and it can sit alongside a training habit rather than replace it. One woman keeps up a demanding class timetable and still notices a fixed slump in the afternoon.

"some slight side effects; tired at 2-3 pm; slightly loose stool. however, i do 5 classes a week at the gym; group fitness, hi intensity and this helps."
– loveshoes1

For others the tiredness arrives first and training simply does not happen. Four days into taking 2.5 mg as a first GLP-1, one poster found the day divided between naps and good intentions.

"The exhaustion has been pretty bad. I have been taking 1-2 hour naps and have been too tired to exercise."
– Number_Ten10

Whether the dip lingers or passes varies from person to person, and the next question is often what appetite does on the days that cardio does happen.


Appetite on Training Days

Exercise and hunger seem to pull in different directions for different people. One person in the second week of the starter dose has noticed that the effect shows up on specific days.

"I noticed that if I do cardio, then my appetite for that day is higher. But for the other days, it’s been a struggle to eat what I am supposed to."
– Smart-Toe-8752

Someone on 2.5 mg describes a similar pairing, offering a tentative explanation without claiming to know.

"On 2.5mg now and still get hungry. I'm working out a lot though, so maybe that's why."
– EntrepreneurBehavior

Fuelling for sessions is a recurring puzzle in its own right, and a commenter three weeks in describes it as something still being worked out.

"I am three weeks in and feeling great now that side effects have leveled out and I’m figuring out strategies for staying hydrated and fueled enough for workouts."
– Ok-Sandwich2365

Before any of that comes a more immediate worry: what happens on the very first morning if there is a class to get to.


The First Class

Anticipation can shape an exercise plan before the first tablet is swallowed. One newcomer had a cardio class booked for the morning after starting and wanted to know how it would go.

"I have a cardio pilates class scheduled for 10:30AM, after a light breakfast around 8ish and would hate to start feeling symptoms during class."
– UnfairCriticism7658

Once the first week had passed, that same poster reported only some reflux and a smaller appetite, while a long-time exerciser in another thread was describing life after months on the tablet.

"I've continued to be a heavy exerciser on Foundayo. Of course my appetite is diminished but I'm still enjoying healthy meals and even small treats."
– inh-exh

The question of whether a class survives the first dose seems to have as many answers as there are people asking it.


Walking, Cycling and Gentler Cardio

Not all cardio is classes and heart-rate zones. For a good many people the realistic version is the treadmill at a steady pace, and they are candid about how modest it can be.

"I walk on the treadmill at least 20 minute, at least 4 times a week (yes I realize more exercise would be beneficial and at the same time, I want to make this experience realistic for myself so I can continue to eat healthy and exercise once I’ve stopped taking Foundayo at some point)."
– sweetpeasplash

At the other end, a gym-goer who takes the tablet on waking and trains straight afterwards describes a daily treadmill session that is considerably longer.

"Then I go to the gym. Over the past three weeks, I've only missed the gym one day. I walk on the treadmill for 65 minutes at a pace where I average 2.8 miles."
– Spiritual_Sea0613

Some people have deliberately turned the dial down. A woman who says she was always very active now chooses walking and cycling, and mentions a side benefit.

"I still prioritize fitness 3-4 days a week (mostly walking and cycling for 40-60 min) but nothing extreme like before. My joints feel so much better too, though that kicked in way before the weight started dropping off."
– Opposite-Hall-5128

That comment about joints turns out to be a theme of its own.


When Lighter Means Different

Several accounts link a changing body to a changing workout. A man whose back once ruled out running describes the shift in two steps.

"I would only walk on the treadmill since running made my back flare up. […] More importantly, with less weight I’m able to exercise more vigorously without hurting my back."
– TwoWas

Another poster draws a similar line around joint pain, and is careful to say they do not know which change deserves the credit.

"As for exercising I didn’t push myself at first but after a few weeks all my joint pain went away. I don’t if it was from change of diet, weightloss or the meds but my knees and ankles used to ache after a few hours at work. Now I zip around all day!!!"
– turtlegray23

For many, the story is less about performance records than about what becomes possible again.


What Does Medino's Pharmacist Think?

"What stands out is how individual this is. Some people say their usual cardio carries on as normal, others describe a slower few weeks, and many settle into a routine that looks quite different from the one they started with."
– Alessandro Grenci, Pharmacist at Medino


Many Ways to Keep Moving

Read together, the accounts describe no single pattern. A steady 20-minute treadmill walk, a high-intensity class and a long daily gym session all appear in the same forums, each person working out for themselves what their body will do on a given day.

Last updated:
Written by Christian Jakobsson
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