Foundayo Not Working: Why You Might Not Feel Anything Yet

You take the first tablet, wait for something to happen, and nothing does. No nausea, no sudden loss of appetite, no quieter thoughts about food. For plenty of people starting Foundayo (orforglipron), that silence is the first thing they notice, and it quickly raises the question of whether the medication is doing anything at all.

Reading through forum threads, the same worry keeps surfacing in different forms: a first day, a first fortnight, a whole month with little to report. These are individual accounts rather than evidence of how often anything happens, but they show how varied the early weeks can look from the inside.


The Silence of the First Few Days

Many people begin with a vague expectation that the pill will announce itself. When it doesn't, the uncertainty can sit oddly alongside the relief of having no side effects.

"Am I doing anything wrong. Am I supposed to feel something?"
– Commercial-Artist911

The answers rarely come from a single day. One person, reporting back after the first tablet, describes the day as unremarkable, with just a hint of tiredness.

"I didn’t feel any different today. Maybe a little tired but otherwise the same"
– UnfairCriticism7658

Not every start is so quiet, which makes the quiet ones feel stranger. A few people report an apparent shift within a couple of days and then wonder whether to trust it.

"I’m convinced it has to be a placebo effect for this to be happening two days in, but I have had absolutely no hunger cravings whatsoever"
– nickd457

Between those two poles sits a more patient reading, from someone who has already worked out how little three days can tell them.

"My guess is I haven’t taken it long enough to feel much of anything, I’m gonna give it time."
– Interesting-Cable895


A Month on the Lowest Dose

Foundayo is started at 0.8 mg and increased in stages, with at least a month at each step, so the earliest weeks are spent on the smallest amount. For some people those weeks pass with almost nothing to show for them.

"One month on 0.8 absolutely nothing happened. No weight loss but no side effects. Started 2.5 one week ago; same."
– loveshoes1

Nothing on the scale is not always nothing at all. Other people in the same position describe small changes that have little to do with weight and are easy to overlook.

"I'm about 3 weeks in on 0.8 and have had almost zero side effects (everything very manageable), but haven't lost any weight really. I am less bloated and I sleep better, though!"
– WatchOut4Sharks

For a few, the change arrives so late in the month that it is easy to miss, and so gently that nobody else would notice.

"It has curbed my appetite but it took a while maybe like nearing the last 5 days of my 0.8 I've noticed I have been eating less. It's also very subtle and not very drastic like for other people."
– Kekandlols


The Explanations That Circulate

When the effect is slow to appear, people reach for reasons, often passed on by a nurse or someone further along. The most common is that the starting dose is a gentle introduction rather than the main event.

"My nurse explained I needed to be patient- that the lowest dose it just a baby dose to get people through the initial phase where nausea can be really bad."
– TwoWas

Some who have moved up describe the same story from the other side, looking back at the early doses as a period when they felt very little.

"0.8mg is a low dose. I didn't feel anything on it. Didn't feel anything on 2.5mg really either. I am feeling it on 5.5mg though."
– EntrepreneurBehavior

Not everyone frames it as an absence. A different group describes the low dose as present but faint, an effect they only recognised in hindsight.

"For me the effect of 0.8 was real but quite mild."
– inh-exh


When Something Changes but the Scale Doesn't

"Working" can mean different things depending on who is asking. One person's post puts the problem plainly: food noise is quieter and eating is well under control, yet the number on the scale has stayed put.

"I upped the dose to 2.5mg this month, and have not lost any additional weight. […] The food noise is reduced, and when I count calories I am around 1100-1300cals. […] My doctor said it could be i am a non responder."
– amazemenot

That gap between what is felt and what is measured appears again and again, and it is not what everyone experiences. At the other end of the spectrum are people who describe a change within a fortnight on the same starting dose.

"I've been on the 0.8 this entire time. The first week was awful - so nauseous I could barely eat anything. The second week I lost all cravings for things - including alcohol and anything snacky."
– Opposite-Hall-5128


When It Still Doesn't Land

Some accounts do not end with a late arrival. Some people describe stepping through the doses, waiting out each month, and still concluding that Foundayo has not done what they hoped.

"Foundayo isn’t working for me. Was at .08 then the 5.5. Now about to start on the Zepbound."
– MobileBlackberry3151

Even there, the story is short and unadorned, a person closing one chapter and opening another without a verdict on anyone else's experience.


What Does Medino's Pharmacist Think?

"What stands out in these accounts is how different the early weeks can look from one person to the next. Some people notice a change almost straight away, some only in hindsight, and some say very little at all. The first weeks can be hard to read, and what someone feels in them is only one part of the picture."
– Alessandro Grenci, Pharmacist at Medino


A Slow Start, Told Many Ways

Put together, these accounts do not point to a single pattern. There are people who feel something on day one, people who feel nothing for a month, people whose appetite changes while the scale stays still, and people who work through the doses without the result they wanted. What they share is the experience of waiting for a signal and trying to decide what the silence means.

Last updated:
Written by Christian Jakobsson
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