User Reviews Unveiled: The Weight Loss Journey with Mounjaro

Reviewed and fact-checked by Alessandro Grenci, Superintendent Pharmacist. Read our editorial policy to see how we create informative, accurate content.

This is an article for those considering Mounjaro for weight loss. As a fairly new medication in the market, we think that it is important to not only understand the clinical and medical aspects of the drug but also what patients can expect. That is what this article will try to answer – what other are saying and sharing about their weight loss journey with Mounjaro. We have collected and analysed more than 750 reviews from real users and condensed them down to key trends in terms of experience, side effects, positive and negative aspects. We will start to look at the review score, then go over key findings, and highlight reviews that stand out to us. Then we will share the expert opinion of our Superintendent Pharmacist before we explore the most common questions associated with Mounjaro for weight loss. Let’s dive in!

Review score

When collecting reviews we looked at the platforms where there is a large enough sample of reviews and where the opinions are both positive and negative in order to portray both positive and negative aspects. The sources used to collect the reviews were and WebMD.


As viewed in the diagram the score is relatively high, above 4/5 on both platforms. Worth mentioning this is higher than the average score for Wegovy, which is also a weight loss treatment with a similar administration. For more info on our customer review analysis, check out our article: Wegovy Reviews

The reviews

Key findings:

  • Major weight loss: A notable number of users have experienced significant weight loss while on Mounjaro, with reports of individuals losing over 60 pounds. This weight loss is particularly beneficial for improving diabetes management and has resulted in some users moving from a classification of morbidly obese to obese on the BMI scale, signaling a positive shift towards healthier weight ranges.
  • Appetite suppression: Mounjaro has been effective in helping users manage their hunger, leading to a decrease in overall caloric intake and a reduction in the frequency of food cravings. This effect aids individuals in adhering to more controlled eating habits, which is instrumental in weight management efforts.
  • Lifestyle changes: Users often highlight the importance of complementing Mounjaro treatment with lifestyle modifications such as adopting healthier eating patterns and incorporating more physical activity into their daily routines. These changes are essential for maximizing the benefits of the medication and achieving long-term health improvements.
  • Improved overall health: Beyond its impact on blood sugar levels, Mounjaro has contributed to a range of health benefits for users, including lower blood pressure, a decrease in the need for insulin, and improvements in cholesterol levels. These changes contribute to a reduced risk of diabetes-related complications and enhance overall well-being.
  • Side effects: While some users report experiencing gastrointestinal side effects such as indigestion, constipation, and nausea, these are typically described as manageable. Strategies like increasing fluid intake and making dietary adjustments have been helpful in mitigating these side effects for many individuals.
  • Injection experience: The process of self-administering Mounjaro injections is generally reported as straightforward and relatively pain-free, with a convenient once-weekly schedule that users find easy to incorporate into their routines.
  • Emotional well-being: The physical improvements and health benefits associated with Mounjaro use have had a positive impact on the emotional well-being of many users. The progress made while on the medication has led to increased confidence and optimism about reaching personal health goals.
  • Supply issues: Access to Mounjaro can be challenging for some individuals. These issues can cause frustration and disrupt the continuity of treatment for those relying on the medication for diabetes management and weight loss.


Positive reviews:

Many patients report significant results. Here are some reviews that show how Mounjaro has helped them in their weightloss journey:

  • Patti, Taken for less than 1 month, February 15, 2024: "For Weight Loss (Obesity/Overweight) 'Just started using it for weight loss. While I'm only on Day 4 and haven't weighed myself, my appetite has decreased significantly... I no longer have a desire to binge-eat.'"
  • Tom, Taken for 6 months to 1 year, February 10, 2024: "For Weight Loss (Obesity/Overweight) 'After years of dealing with type 2 diabetes and taking metformin, I finally managed to get my numbers under control... At the age of 68, after about 15 years of being quite obese... I started with a low-dose weekly injection and in a few months worked my way up to the full recommended dosage of 15 MG/0.5ML per week. It's been less than a year and I have lost 110 lbs and feel fantastic with no noticeable side effects.'"
  • ADD, Taken for 6 months to 1 year, February 8, 2024: "For Weight Loss (Obesity/Overweight) 'I have lost 73 lbs in 7 months. I am not hungry, cranky, normal energy levels. I eat what I want, just greatly reduced portions and I am full. Fried & processed foods no longer taste good and I naturally migrate to healthier foods, fruits & veggies.'"
  • Gamec, Taken for 1 to 6 months, February 3, 2024: "For Weight Loss (Obesity/Overweight) 'I'm on my 6th dose as of today... I have lost 12 lbs so far... In my 40s, I was always slim, but in my 60s, my weight became a problem... As I continue with the medication, I am learning about what foods I can and cannot eat due to the side effects.'"
  • Murphy, Taken for 1 to 6 months, February 2, 2024: "For Weight Loss (Obesity/Overweight) 'Nausea and headache. Can only eat small meals or foods at one time. Losing weight all over, legs, waist, around back. It’s done amazing changes for me and weight loss of 40 lbs.'"
  • BuzzP, Taken for 6 months to 1 year, February 3, 2024: "For Weight Loss (Obesity/Overweight) 'Mounjaro has been a blessing to me. I'm a 70-year-old male who was previously obese, had high blood pressure, high cholesterol, and type 2 diabetes... I've had 2 heart attacks and received stents, as well as a knee replacement. I started with a low-dose weekly injection and in a few months worked my way up to the full recommended dosage... It's been less than a year and I have lost 110 lbs and feel fantastic with no noticeable side effects.'"
  • Norma, Taken for 6 months to 1 year, February 1, 2024: "For Weight Loss (Obesity/Overweight) 'Good loss of appetite, can't usually eat my entire meal so willpower from heaven when choosing my food... Only side effect is after injection I will feel nausea for a day and a half and usually have antisickness pills to take.'"

Negative reviews:

Most of the negative reviews are centred around the side effects associated with the treatment. Here are some of the negative reviews that stood out to us.

  • Anonymous, Condition: Other, Overall rating 1.7: "Started this at 2.5 mg dose for weight loss. Weight 173lbs one week later 165lbs. The worst nausea vomiting and diarrhea. No desire to eat food. On day 5 woke up with chest pain my heart rate was 65-128bpm. Ended up in the ER with full cardiac work up. Abnormal EKG. I’m 58years old. Today had to have more cardiac testing and now have a cardiologist. Advised to stop the medication. I paid a big price for 8lb loss."
  • Dawn, 55-64, Taken for less than 1 month: "i started this shot on a tues and immediately had dry mouth and no appetite. by the third day my muscles and joints hurt so badly i could hardly move... ended up in hospital getting fluid iv. while i did lose 15 lbs in a little under 2 weeks i couldn't function."
  • Grettle, 45-54, Taken for less than 1 month: "Extreme vomiting and diarrhea simultaneously and this was on day two of merely 2.5mg... I think I lost everything inside of me."
  • Anonymous, 45-54, Taken for less than 1 month: "I did one injection and broke out in an extreme rash... the rash keeps getting worse... Hopefully that will happen sooner than later."
  • Nonomon, 45-54, Taken for less than 1 month: "1st injection taken late afternoon. Woke up the next morning projectile vomiting...yeah. 2 days of vomiting and body pain everywhere to almost going to E.R."
  • Slim, 55-64, Taken for less than 1 month: "I have taken this medication on Sunday and started to get side effects on Tuesday... Imodium won't stop my diarrhea and my nausea feels like it did when I was pregnant."
  • Dawna, 45-54, Taken for less than 1 month: "I have had the worst experience with this medication if it had a side effect I have had it times 10... Ended up in hospital getting fluid iv... I will NOT be taking a second dose of this medication."

Pharmacist comment

We spoke to our Superintenden Pharmacsit, Alessandro Grenci, about the launch of Mounjaro for weight loss:

As a pharmacist, I'm excited to introduce Mounjaro, a new product in the market that has shown to be effective in the battle against obesity. What sets Mounjaro apart is its weekly dosage regimen, which simplifies the treatment process for patients. It's important for those interested in this innovative solution to know that Mounjaro can be purchased directly from the pharmacy, under the supervision of a pharmacist, ensuring safe and informed use.

Mounjaro for Weight Loss: Frequently Asked Questions

Finally, we went through the most commonly asked questions about Mounjaro, here answered by Alessandro, Superintendent Pharmacist.

What is Mounjaro?

Mounjaro is a medication initially approved for treating type-2 diabetes. It contains the active ingredient tirzepatide and works by mimicking the function of hormones GLP-1 and GIP, which regulate insulin production and glucose levels. It has also been shown to aid in weight loss.

How does Mounjaro work for weight loss?

Mounjaro promotes weight loss by reducing appetite, slowing the movement of food through the stomach, and affecting how the body handles insulin and glucose. This can lead to a decrease in calorie consumption and weight loss.

What are the common side effects of Mounjaro?

Common side effects include nausea, diarrhoea, decreased appetite, vomiting, constipation, indigestion, and stomach pain. These side effects are more prevalent during dose increases and tend to decrease over time.

How is Mounjaro administered?

Mounjaro is a once-weekly injectable medication that can be administered in the stomach, thigh, or the back of the arm by the patient or another person. It's important to rotate the injection site with each dose.

What should I eat while taking Mounjaro?

While there isn’t a specific diet plan recommended, following a healthy and balanced diet is crucial. This includes consuming plenty of vegetables, fruits, lean proteins, and whole grains while avoiding processed and fried foods.

Can Mounjaro be used in combination with other medications?

Mounjaro can be used alongside other medications, but it's essential to consult with a healthcare provider to avoid any potential interactions, especially if you're taking medications for diabetes management.

How much weight can I expect to lose with Mounjaro?

Weight loss is highly variable among individuals. On average, an individual can expect to lose 20% of their total body weight in a little over a year when combining Mounjaro with a healthy lifestyle.

What happens if I don't lose weight on Mounjaro?

Weight loss is a complex process, and results may vary. If you're not seeing the desired results, it's important to discuss with your doctor possible adjustments to your treatment plan or exploring other options.

Is Mounjaro safe for children?

Mounjaro is not approved for use in individuals under 18 years of age. Its safety and effectiveness in children have not been established.

How should Mounjaro be stored?

Mounjaro pens should be stored in the refrigerator until use.

That concludes our article on Mounjaro for weight loss. If you have any further questions, feel free to reach out to us: Contact us. If you would like to browse our Mounjaro range you can visit the Mounjaro products page.

Written by Christian Jakobsson