Can Mounjaro or Wegovy reduce cravings for alcohol or other substances?

Mounjaro, used for weight loss, shows promising signs of reducing alcohol cravings by mimicking hormones that quieten brain signals for hunger and addictive urges. User reports and early studies, including rodent tests and human trials on similar drugs, indicate it may lower desire for alcohol, especially in people with obesity, though full human studies for addiction are ongoing. Evidence for other substances is limited but suggests similar effects on cravings due to how these drugs affect the brain.

Promising for alcohol cravings: 71% of users in a Reddit analysis reported less desire to drink on Mounjaro or similar drugs; trials show reduced heavy drinking in obese patients.
Early research support: Rodent studies confirm GLP-1 drugs like Mounjaro's tirzepatide cut alcohol intake; human trials needed for confirmation.
Limited for other substances: Some evidence points to broader addiction help, but more studies are required; not approved for this use.

This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.