Do antihistamines affect blood pressure?

Antihistamines on their own do not raise blood pressure. Second-generation types, which are non-sedating, are safe for people with high blood pressure. However, some combination products with added ingredients like decongestants can increase blood pressure.

Key points:

  • Antihistamines alone have little or no effect on blood pressure.
  • Second-generation antihistamines are safe for those with high blood pressure.
  • First-generation sedating antihistamines may cause dizziness or low blood pressure in some cases.
  • Products combining antihistamines with decongestants can raise blood pressure.

This text has been fact-checked for accuracy by medino's clinical team.