Does L-arginine work for erectile dysfunction?

L-arginine supplementation shows some evidence of improving erectile dysfunction, particularly in mild to moderate cases caused by blood vessel problems, when taken at high doses like 5 grams daily for three months. Studies indicate modest benefits compared to placebo, with better results in combinations with other treatments than L-arginine alone, though it is less effective than standard ED medications. Evidence is mixed and more research is needed for stronger conclusions.

Key points:

  • High-dose L-arginine improves erectile function scores in mild-moderate vasculogenic ED.
  • Benefits are modest and more evident in mild cases than severe ED.
  • L-arginine alone is less effective than PDE5 inhibitors for ED.
  • Evidence from trials is mixed, with calls for more research.

This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.