Does Wegovy improve insulin resistance in PCOS?

Wegovy, a weight loss medication containing semaglutide, can improve insulin resistance in people with PCOS mainly through promoting weight loss. Studies show that losing 5-10% of body weight with Wegovy reduces insulin resistance by making cells more responsive to insulin. It is not approved specifically for PCOS or insulin resistance, but is sometimes prescribed off-label for weight management in this group.

Key points:

  • Wegovy aids weight loss, which lowers insulin resistance in PCOS.
  • Research shows semaglutide improves insulin sensitivity and blood sugar control.
  • Nearly 80% of patients with PCOS and obesity lost significant weight and saw metabolic benefits.
  • Weight loss from Wegovy indirectly helps PCOS-related insulin issues.

This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.