How can I reduce my risk of developing gallstones on GLP-1 medications?
To reduce your risk of developing gallstones on GLP-1 medications, aim for steady, gradual weight loss rather than rapid or large losses, as weight loss itself is a key driver of gallstone formation. If you are losing weight very quickly or have troublesome side effects that reduce food or fluid intake, speak to your prescriber to review your plan (including whether dose adjustments or closer monitoring are needed).
Key points:
- Steady weight loss helps lower gallstone risk compared with rapid weight loss.
- Discuss review/monitoring if weight loss is very fast or side effects are significant.
- Higher doses and longer treatment duration have been associated with more gallbladder events in some studies.
This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.