Is it safe to combine Wegovy with other weight loss medications?
No, combining Wegovy with other weight loss medications is not recommended in UK practice. The main reason is that there is insufficient evidence for the safety and effectiveness of such combinations, and the risk of overlapping side effects may increase. Current NHS guidance and NICE recommendations emphasize using Wegovy as a standalone treatment alongside lifestyle support rather than in combination with other anti-obesity drugs.
Key points:
- Combining weight loss medications can magnify side effects without clear added benefit, as different drugs may affect overlapping body systems.
- UK regulators and prescribers follow a cautious approach because large clinical trials testing combinations have not been conducted.
- Wegovy is prescribed only within specialist weight-management services, where clinicians review all medications to identify potential interactions and prioritize safety.
- If you are taking other medicines, particularly for conditions like type 2 diabetes, your prescriber will coordinate care to avoid risks such as low blood sugar.
This text has been fact-checked for accuracy by Alessandro Grenci, Superintendent Pharmacist at medino.