Is it safe to switch between GLP-1 medications?

Switching between GLP-1 medications, including to or from Mounjaro for weight loss, can be safe when done under the supervision of a healthcare professional. The process may involve careful timing of doses and monitoring for side effects, as different GLP-1 medicines can affect people in different ways. In the UK, you should only switch GLP-1 treatments if prescribed and guided by a doctor, who will assess your health needs and ensure the change is appropriate.

Always consult your doctor or prescriber before switching GLP-1 medications, including to or from Mounjaro.
Switching may involve a short gap between treatments, depending on the medicines involved and individual circumstances. This is typically a week between Mounjaro and Wegovy and 2 days between these and Saxenda.
Side effects such as nausea or stomach upset can occur during a switch; report any severe or persistent symptoms to your healthcare team.
GLP-1 medicines should only be used when clinically prescribed for weight management or diabetes.
Your clinician will advise on the safest way to switch, monitor your progress, and help manage any side effects.

This content has been fact-checked for accuracy by Alessandro Grenci, Superintendent Pharmacist at medino.

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