Is it safe to take Mounjaro with blood pressure medications?

It is usually safe to take Mounjaro (tirzepatide) with blood pressure medicines. However, weight loss and improved metabolic health can lower your blood pressure over time, and Mounjaro can also cause nausea, vomiting, or diarrhoea in some people, which may lead to dehydration and a drop in blood pressure. Your prescriber may need to monitor your readings and adjust your blood pressure treatment if you develop symptoms of low blood pressure.

Key points:

  • Mounjaro may lower blood pressure over time, so your blood pressure medicines may need review.
  • The main risk is low blood pressure, especially if you have reduced fluid intake or diarrhoea or vomiting.
  • Extra caution is needed with diuretics, as dehydration can increase the risk of dizziness, fainting, or kidney strain.
  • Tell your GP or prescriber about all medicines you take, and check your blood pressure more often when starting or increasing the dose.

This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.