Is Mounjaro more effective than Wegovy for people with high BMI?
Clinical trials show Mounjaro leads to slightly greater average weight loss than Wegovy, with up to 22.5% of starting body weight lost after 72 weeks on Mounjaro's highest dose compared to around 15-21% for Wegovy over similar periods. These results come from studies involving people with obesity or high BMI, though direct head-to-head comparisons are limited. Both medications are highly effective for weight loss when used as prescribed alongside diet and exercise.
Key points:
- Mounjaro achieves up to 22.5% average weight loss after 72 weeks in trials.
- Wegovy achieves 15-21% average weight loss after 68-72 weeks in trials.
- Mounjaro shows slightly superior results, especially at higher doses.
- No direct comparison trials exist between the two drugs.
This text has been fact-checked for accuracy by Alessandro Grenci, Superintendent Pharmacist at medino.