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Should I take antihistamines before bed or in the morning?

The best time to take antihistamines depends on the type and when your symptoms are worst. Take drowsy types like diphenhydramine before bed to avoid daytime sleepiness and help with night symptoms. Non-drowsy types like loratadine work well in the morning for all-day cover against daytime symptoms.

Key points:

• Drowsy antihistamines suit bedtime dosing to match their sleep-causing effect.
• Non-drowsy antihistamines fit morning use for daytime symptom control.
• Bedtime dosing cuts morning symptoms by working overnight.
• Morning dosing gets ahead of peak pollen later in the day.

This text has been fact-checked for accuracy by medino's clinical team.