Why do some people experience irregular periods when taking GLP-1 medications?

Some people experience irregular periods when taking GLP-1 medications due to rapid weight loss that alters hormone production. These medications also improve insulin sensitivity, which can temporarily disrupt cycles as the body adjusts. Changes in stress levels from lifestyle shifts linked to the medication and weight loss can further contribute to irregularity.

Key points:

  • Rapid weight loss from GLP-1 medications affects estrogen and progesterone levels.
  • Improved insulin sensitivity causes temporary cycle adjustments.
  • Stress responses to weight changes disrupt menstrual timing.
  • Body fat reduction alters hormone release from fat cells.

This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.