What is Skinoren

Skinoren® 20% Cream (azelaic acid) is a topical treatment for mild to moderate acne vulgaris. It works by reducing the formation of comedones (blackheads and whiteheads) and targeting acne-causing bacteria (Propionibacterium acnes), leading to clearer skin and reduced inflammation. Visible improvement usually occurs after around 4 weeks, with best results achieved through consistent use over several months.

Who is Skinoren for

Skinoren® is intended for individuals aged 12 years and above who meet specific criteria:

1. Confirmed acne diagnosis For those presenting with mild to moderate acne vulgaris, as defined by NICE guidelines, any number of comedones, up to 34 inflammatory lesions, and up to 2 nodules.
2. No complicating skin conditions Not suitable for patients with severe acne or complicating dermatological conditions (e.g. acne conglobata, acne fulminans, rosacea, or perioral dermatitis).
3. Preference for private access For those who prefer to access treatment through a pharmacist-led consultation rather than a GP appointment.

Consultation process

Your treatment will be supplied under a Patient Group Direction (PGD), not a traditional prescription. The process includes the following steps:

1. Complete an online health questionnaire

Provide details about your acne symptoms, medical history, and any prior treatments.

2. Pharmacist assessment

A pharmacist authorised under this PGD will review your responses and will contact you by phone or video call to confirm eligibility.

3. Private consultation

All consultations are confidential and allow you to ask questions to ensure Skinoren® is appropriate for you.

4. All-inclusive pricing

The consultation fee is included in the total price. No hidden costs.

5. Identity verification

First-time patients will be asked to verify their identity to ensure safe and appropriate supply.

6. GP or record consent if required

If clarification is needed, consent to contact your GP or review medical records may be requested.

For patients with uncertain diagnosis, severe acne, or acne leading to scarring or pigmentary changes, referral to a GP or specialist is advised.

Patient Information Leaflet

• Active Ingredient: Azelaic acid (20% w/w)
• Excipients:
  • Benzoic acid (E210)
  • Cetearyl octanoate and isopropyl myristate (PCL Liquid)
  • Glycerol 85%
  • Glycerol monostearate 40-55,
  • Cetostearyl alcohol
  • Propylene glycol
  • Purified water
  • Stearoyl macrogolglycerides

Skinoren® 20% Cream should be applied to the affected areas of the skin twice daily, once in the morning and once in the evening.

For patients with sensitive skin, it is recommended to start with a single application in the evening for the first week. Before applying the cream, cleanse the skin with plain water or a mild cleanser and dry it thoroughly. A pea-sized amount should be applied and gently massaged into the skin. The duration of treatment varies, but noticeable improvement usually occurs within 4 weeks. For optimal results, the cream should be used continuously over several months but should not exceed 12 months of use.

• May cause mild skin irritation, especially during the first few weeks of treatment. If irritation occurs, reduce application frequency or pause use temporarily.
• Do not combine with other topical acne treatments unless advised by a healthcare professional.

Contraindications

• Known hypersensitivity to azelaic acid or any excipients in the formulation.
• Under 12 years of age.
• Pregnancy or breastfeeding unless specifically recommended by a healthcare professional.
• Presence of rosacea, perioral dermatitis, or other non-acne inflammatory skin conditions.
• Severe acne (e.g. acne conglobata or acne fulminans).
• Application to sunburned, irritated, or recently treated skin (chemical peels, laser, or similar procedures).
• Avoid contact with eyes, mouth, and mucous membranes.

• Common Side Effects:
  • Burning sensation at the application site
  • Itching (pruritus)
  • Erythema (redness of the skin)
  • Dryness or peeling of the skin
• Uncommon Side Effects:
  • Seborrhea (excessive oiliness)
  • Acne exacerbation
  • Skin depigmentation
  • Contact dermatitis
  • Discomfort at the application site
• Rare Side Effects:
  • Cheilitis (inflammation of the lips)
  • Vesicles (small blisters)
  • Exacerbation of asthma

If you experience severe side effects or if symptoms persist, discontinue use and consult your GP or a healthcare professional. Report any adverse effects via the MHRA Yellow Card scheme.

For more information, please refer to the Patient Information Leaflet.