Numark Fluconazole 150mg Capsule is a pharmacy medicine for the treatment of thrush, containing fluconazole 150 mg in a hard capsule for oral use.

Fluconazole is an antifungal medicine from a group called azoles. It works against the fungus responsible for thrush. The medicine is licensed for candidal vaginitis, including acute or recurrent vaginal thrush, and may also be used for associated candidal balanitis in a sexual partner.

For adults aged 16 to 60 years, the full course consists of one 150 mg capsule taken as a single dose. The capsule should be swallowed whole with a glass of water and can be taken with or without food.

Only use this medicine if you have previously been told by a doctor that you have thrush. If symptoms have not improved within 7 days, seek medical advice.

This is a pharmacy medicine. A pharmacist may provide advice about its appropriate use where required.

Read the Patient Information Leaflet before use.

Main ingredient: Fluconazole 150 mg per capsule.

Numark Fluconazole 150mg Capsule is used for the treatment of thrush, including candidal vaginitis and associated candidal balanitis.

Adults aged 16 to 60 years: Take one 150 mg capsule as a single dose.

The capsule should be swallowed whole with a glass of water. It can be taken with or without food.

Under 16 years or over 60 years: Do not use without first speaking to a doctor.

The single capsule represents the full course of treatment. If more than one capsule is taken, contact a doctor straight away or attend the nearest Accident and Emergency Department.

The leaflet states that symptoms of thrush should usually disappear within 2 days. If there is no improvement after 7 days, tell your doctor.

If the infection returns after 7 days, another capsule may be taken. If you have more than two episodes of thrush within 6 months, speak to a doctor.

No missed-dose instructions are required because this medicine is taken as a single dose.

Do not take Numark Fluconazole 150mg Capsule if you:

• Are allergic to fluconazole, another azole antifungal or any of the other ingredients.
• Are taking astemizole or terfenadine for allergies.
• Are taking cisapride.
• Are taking pimozide.
• Are taking quinidine.
• Are taking erythromycin.
• Are taking ergot derivatives such as ergotamine.
• Have tinea capitis, a fungal infection of the scalp.

Speak to a doctor or pharmacist before use if:

• You are under 16 or over 60 years of age.
• You have had thrush more than twice in the last 6 months.
• This is the first time you have experienced these symptoms or you are unsure whether you have thrush.
• You have liver or kidney problems or have previously had unexplained jaundice.
• You have heart disease or a heart rhythm problem.
• You have low potassium, magnesium or calcium levels.
• You have another chronic illness.
• You or your partner may have been exposed to a sexually transmitted infection.

Women: Do not use this medicine and seek medical advice if you have irregular or abnormal vaginal bleeding, blood-stained discharge, ulcers, blisters or sores of the vagina or vulva, lower abdominal pain, pain or difficulty passing urine, or foul-smelling vaginal discharge.

Men: Speak to a doctor before use if your sexual partner does not have thrush, or if you have pain or difficulty passing urine, abnormal penile discharge, sores, ulcers or blisters on the penis, or an unusual smell from the penis.

Interactions: Tell your doctor or pharmacist about other medicines you take. Fluconazole can interact with medicines including anticoagulants such as warfarin, medicines for heart rhythm problems, some blood pressure medicines, diabetes medicines, statins, anti-epileptic medicines, benzodiazepines, immunosuppressants, some antibiotics and antifungals, halofantrine, theophylline, opioid painkillers, NSAIDs, some antidepressants, HIV medicines and some medicines used for cancer.

Pregnancy: Do not take fluconazole if you are pregnant, think you may be pregnant or are trying to become pregnant unless your doctor has told you to. If planning a pregnancy, the product information recommends waiting 1 week after a single dose before becoming pregnant.

Breastfeeding: Ask your doctor or pharmacist for advice before use. The SmPC states that breastfeeding may be continued following a single 150 mg dose of fluconazole.

Alcohol: The leaflet states that there is no known interaction with alcohol.

Driving and using machines: Fluconazole may cause dizziness or seizures. Do not drive or operate machinery if you experience these effects.

This medicine contains lactose. It also contains methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216), which may cause allergic reactions, possibly delayed.

Stop taking the medicine and seek medical attention immediately if you develop a severe allergic reaction, widespread rash, blistering or peeling skin, swelling of the face or lips, or symptoms of DRESS such as widespread rash, high temperature and enlarged lymph nodes.

Fluconazole can rarely cause serious liver problems. Seek medical advice immediately if you develop marked tiredness, loss of appetite, vomiting, dark urine, pale stools or yellowing of the skin or whites of the eyes.

Overdose: If you take more than one capsule, tell a doctor straight away or contact the nearest Accident and Emergency Department.