Nuromol Pain Relief 200mg/500mg Film Coated Tablets provide temporary relief of mild to moderate pain in adults aged 18 years and over.

Each film-coated tablet contains ibuprofen 200 mg and paracetamol 500 mg. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain, swelling and high temperature, while paracetamol is an analgesic that works in a different way to relieve pain and fever.

Nuromol can be used for migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, pain associated with non-serious arthritis, cold and flu symptoms, sore throat and fever. The medicine is particularly suitable for pain that has not been relieved by ibuprofen or paracetamol alone.

The usual dose is one tablet with water and food, up to three times a day, leaving at least 6 hours between doses. If one tablet does not control symptoms, up to two tablets may be taken at a time. Do not take more than 6 tablets in 24 hours or use for longer than 3 days.

This is a pharmacy medicine. A pharmacist may provide advice about its appropriate use where required.

Patient Information Leaflet

Main ingredients: Ibuprofen 200 mg and paracetamol 500 mg per film-coated tablet. Excipients: Croscarmellose sodium, microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, stearic acid, polyvinyl alcohol, titanium dioxide, talc, macrogol, potassium aluminium silicate (E555), polysorbate.

Nuromol Pain Relief 200mg/500mg Film Coated Tablets are used for the temporary relief of mild to moderate pain, including migraine, headache, backache, period pain, dental pain, rheumatic and muscular pain, pain of non-serious arthritis, cold and flu symptoms, sore throat and fever.

Adults aged 18 years and over: Take 1 tablet with water and food, up to three times a day.

Leave at least 6 hours between doses.

If one tablet does not control symptoms, a maximum of 2 tablets may be taken at one time, up to three times a day.

Maximum daily dose: 6 tablets in any 24-hour period, equivalent to 1,200 mg ibuprofen and 3,000 mg paracetamol.

Do not use in anyone under 18 years of age.

For oral use and short-term use only. Use the lowest effective dose for the shortest time necessary to relieve symptoms.

Do not take this medicine for longer than 3 days. If symptoms persist or worsen, consult a doctor.

Taking the tablets with food is recommended to reduce the likelihood of side effects.

If you forget a dose, take it when you remember and leave at least 6 hours before the next dose. Do not take a double dose to make up for a forgotten dose.

If you are taking this medicine for an infection and symptoms such as fever or pain persist or worsen, consult a doctor without delay.

Do not take Nuromol Pain Relief if you:

• Are taking another medicine containing paracetamol.
• Are taking another NSAID, including ibuprofen, high-dose aspirin above 75 mg daily or a COX-2 inhibitor.
• Are allergic to ibuprofen, paracetamol, aspirin, other NSAIDs or any of the other ingredients.
• Have or have previously had a stomach or duodenal ulcer or gastrointestinal bleeding.
• Have a blood clotting disorder.
• Have heart, liver or kidney failure.
• Are in the last 3 months of pregnancy.
• Are under 18 years of age.

Speak to a doctor or pharmacist before taking this medicine if you are elderly or have asthma, kidney, heart, liver or bowel problems, systemic lupus erythematosus, another connective tissue disorder, ulcerative colitis, Crohn's disease, high blood pressure, diabetes or high cholesterol, or if you smoke.

Ibuprofen may be associated with a small increased risk of heart attack or stroke, particularly when taken at high doses. Do not exceed the recommended dose or treatment duration.

This medicine can hide symptoms of an infection, including fever and pain. If symptoms of an infection persist or worsen, consult a doctor without delay.

Serious skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS and acute generalised exanthematous pustulosis have been reported. Stop taking the medicine and seek immediate medical attention if you develop a severe or widespread rash, blistering, peeling skin, sores affecting the mouth, eyes or genitals, or a rash accompanied by fever.

Tell your doctor or pharmacist about other medicines you take. Important interactions include anticoagulants such as warfarin, corticosteroids, certain antibiotics including flucloxacillin, anti-sickness medicines, medicines for high blood pressure, diuretics, cardiac glycosides, lithium, SSRIs, methotrexate, ciclosporin, tacrolimus, cholestyramine, mifepristone, zidovudine and isoniazid.

Pregnancy: Do not take this medicine during the last 3 months of pregnancy. During the first 6 months, it should only be used if absolutely necessary and advised by a doctor. From 20 weeks of pregnancy, use for more than a few days may affect the unborn baby's kidneys or a blood vessel in the baby's heart.

Breastfeeding: The SmPC states that breastfeeding does not need to be interrupted during short-term treatment at the recommended dose. Speak to a doctor or pharmacist if you are breastfeeding and are unsure whether this medicine is appropriate.

Ibuprofen may temporarily make it more difficult to become pregnant. This effect is reversible after stopping the medicine.

Driving and using machines: Dizziness, drowsiness, tiredness and visual disturbances can occur. Do not drive or operate machinery if affected.

Alcohol: Excessive or chronic alcohol consumption may increase the potential for paracetamol-related liver harm.

Allergic reactions: Stop taking the medicine and seek immediate medical attention if you develop breathing difficulties, worsening asthma, or swelling of the face, tongue, throat or neck.

This medicine is essentially sodium free, containing less than 1 mmol sodium (23 mg) per dose.

Overdose: If you take more than the recommended amount, contact a doctor or the nearest hospital immediately, even if you feel well. Too much paracetamol can cause delayed, serious liver damage. Possible overdose symptoms include nausea, stomach pain, vomiting, headache, ringing in the ears, confusion, drowsiness, chest pain, palpitations, loss of consciousness, convulsions, dizziness, blood in the urine and breathing problems.

Do not take Nuromol Pain Relief if you:

• Are taking another medicine containing paracetamol.
• Are taking another NSAID, including ibuprofen, high-dose aspirin above 75 mg daily or a COX-2 inhibitor.
• Are allergic to ibuprofen, paracetamol, aspirin, other NSAIDs or any of the other ingredients.
• Have or have previously had a stomach or duodenal ulcer or gastrointestinal bleeding.
• Have a blood clotting disorder.
• Have heart, liver or kidney failure.
• Are in the last 3 months of pregnancy.
• Are under 18 years of age.

Speak to a doctor or pharmacist before taking this medicine if you are elderly or have asthma, kidney, heart, liver or bowel problems, systemic lupus erythematosus, another connective tissue disorder, ulcerative colitis, Crohn's disease, high blood pressure, diabetes or high cholesterol, or if you smoke.

Ibuprofen may be associated with a small increased risk of heart attack or stroke, particularly when taken at high doses. Do not exceed the recommended dose or treatment duration.

This medicine can hide symptoms of an infection, including fever and pain. If symptoms of an infection persist or worsen, consult a doctor without delay.

Serious skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS and acute generalised exanthematous pustulosis have been reported. Stop taking the medicine and seek immediate medical attention if you develop a severe or widespread rash, blistering, peeling skin, sores affecting the mouth, eyes or genitals, or a rash accompanied by fever.

Tell your doctor or pharmacist about other medicines you take. Important interactions include anticoagulants such as warfarin, corticosteroids, certain antibiotics including flucloxacillin, anti-sickness medicines, medicines for high blood pressure, diuretics, cardiac glycosides, lithium, SSRIs, methotrexate, ciclosporin, tacrolimus, cholestyramine, mifepristone, zidovudine and isoniazid.

Pregnancy: Do not take this medicine during the last 3 months of pregnancy. During the first 6 months, it should only be used if absolutely necessary and advised by a doctor. From 20 weeks of pregnancy, use for more than a few days may affect the unborn baby's kidneys or a blood vessel in the baby's heart.

Breastfeeding: The SmPC states that breastfeeding does not need to be interrupted during short-term treatment at the recommended dose. Speak to a doctor or pharmacist if you are breastfeeding and are unsure whether this medicine is appropriate.

Ibuprofen may temporarily make it more difficult to become pregnant. This effect is reversible after stopping the medicine.

Driving and using machines: Dizziness, drowsiness, tiredness and visual disturbances can occur. Do not drive or operate machinery if affected.

Alcohol: Excessive or chronic alcohol consumption may increase the potential for paracetamol-related liver harm.

Allergic reactions: Stop taking the medicine and seek immediate medical attention if you develop breathing difficulties, worsening asthma, or swelling of the face, tongue, throat or neck.

This medicine is essentially sodium free, containing less than 1 mmol sodium (23 mg) per dose.

Overdose: If you take more than the recommended amount, contact a doctor or the nearest hospital immediately, even if you feel well. Too much paracetamol can cause delayed, serious liver damage. Possible overdose symptoms include nausea, stomach pain, vomiting, headache, ringing in the ears, confusion, drowsiness, chest pain, palpitations, loss of consciousness, convulsions, dizziness, blood in the urine and breathing problems.