Ovesse 1mg/g Estriol Vaginal Cream 15g is a low dose local HRT cream. It helps ease vaginal dryness, soreness, itching, burning and pain with sex linked to menopause. As it acts mainly in the vagina, whole body hormone levels stay low for most users. Many women who need targeted relief may find this option feels more precise and calm. Studies of estriol vaginal use show clear gains in comfort, moisture and tissue health. This cream may suit postmenopause users who want local care with clear, tried effect.

Key Features

• Targeted vaginal relief: Helps ease dryness, sore skin, itch, burn and painful sex from low oestrogen.
• Local hormone action: Works mainly in the vagina, with low spread to the rest of the body.
• Evidence based choice: Estriol vaginal care shows strong gains for atrophy signs and daily comfort.
• Helps vaginal health: Aids tissue repair, pH balance and friendly flora, so guards against soreness.
• OTC pharmacy access: Sold in UK pharmacies with checks to support safe use.
• Simple cream format: Comes as a small 15g tube plus applicator for neat, direct use.

What symptoms can Ovesse help with?

This cream aims to ease key signs of genitourinary syndrome of menopause in the vagina. Many users note less dryness, soreness, itch, burning and pain with sex over time. Some women also experience fewer urine leaks or cystitis episodes once tissue strength improves. Each body is unique, so effect speed and depth can vary.

Who is Ovesse 1mg/g Estriol Vaginal Cream for?

This cream is for women aged fifty or more who are at least one year post-menopause. It is aimed at those with clear vaginal menopause symptoms who want local HRT care. Women with a history of breast cancer, clotting disorders or other high-risk conditions must seek clinical advice before use. A review with a GP or menopause specialist can help weigh risks and expected benefit.

How does Ovesse work in the body?

The cream contains estriol, a milder form of the oestrogen hormone, in a low dose. Once applied in the vagina, it absorbs into the thin tissue and promotes cell growth. The lining becomes thicker, more moist and more resilient, and the vaginal pH shifts to a more protective range. Over weeks, this may reduce friction, ease pain and support urinary tract health.

How long does it take to notice a difference?

Many women feel some relief of dryness or burning within a few weeks. Full improvement in tissue strength, moisture and pH may take longer. As symptoms stabilise, some users move to a lower ongoing maintenance schedule. Regular review with a clinician helps ensure safe and appropriate use.

Apply using the supplied applicator.

Initial dose: one applicator filled to the red ring once daily for two weeks.

Maintenance dose: one applicator filled to the red ring twice weekly with three to four days between doses.

For vaginal use only. Clean the applicator with warm soapy water after each use.

Do not boil.

Do not use if you have or have had breast cancer, ovarian or womb cancer, unexplained vaginal bleeding, blood clots, liver disease, porphyria or allergy to any ingredient.

Stop use and seek medical advice if you develop new vaginal bleeding, itching, symptoms of infection or signs of an allergic reaction.

Discuss use with a healthcare professional if you have risk factors for blood clots, endometrial conditions, liver disorders, diabetes, migraines, lupus, asthma or high triglycerides.

Not suitable during pregnancy or breast-feeding.

If undergoing surgery, you may need to stop treatment four to six weeks beforehand.

Common effects include vaginal irritation, itching or discharge, spotting or bleeding, headache, nausea, breast tenderness and skin reactions.

Rare but serious allergic reactions may occur.

Systemic risks associated with higher dose HRT, such as blood clots, stroke or gallbladder disease, are considered lower with local vaginal therapy but cannot be ruled out.

Report any adverse effects to a healthcare professional or through the Yellow Card Scheme.