Can Mounjaro affect contraceptive effectiveness?
Yes, Mounjaro (tirzepatide), used for weight loss, can reduce the effectiveness of oral contraceptive pills in some women, especially those who are overweight. UK health authorities recommend using an additional or alternative non-oral contraceptive method, such as an implant, coil, or condoms, particularly during the first four weeks of starting Mounjaro or after any dose increase. Women are also advised not to use Mounjaro during pregnancy, while trying to conceive, or while breastfeeding, due to limited safety data.
- Mounjaro may lower the effectiveness of the oral contraceptive pill.
- UK regulators advise using a non-oral contraceptive (implant, IUD, condoms) with Mounjaro.
- Extra contraception is especially important for four weeks after starting or increasing the dose.
- Do not use Mounjaro if pregnant, trying to get pregnant, or breastfeeding.
- Consult your healthcare provider for personalised advice before starting Mounjaro if you use contraception.
This text has been fact checked for accuracy by Alessandro Grenci, Superintendent Pharmacist at medino.