What happens in your body if you skip doses of Wegovy?
Skipping doses of Wegovy (semaglutide) causes the level of medication in your body to fall, which can reduce its effectiveness for weight management. Wegovy is designed to be taken once weekly to maintain consistent appetite suppression and feelings of fullness. Missing one or more doses may lead to increased hunger, stronger cravings, and slower or stalled weight loss. If treatment is interrupted for several weeks, restarting may increase the chance of side effects such as nausea, as your body needs time to readjust. In the UK, guidance advises taking a missed dose within 5 days if possible; if more than 5 days have passed, the missed dose should be skipped and the next dose taken as scheduled.
- Appetite control and fullness may reduce when Wegovy levels drop
- Weight loss may slow or become inconsistent if doses are missed
- Side effects may be more likely when restarting after a longer break
- A missed dose can be taken within 5 days; otherwise, skip and continue as normal
- Do not double doses, and seek medical advice if more than one dose is missed
This text has been fact-checked for accuracy by Sorin Romaniuc, Pharmacist at medino.