Pure Encapsulations Adenosyl/Hydroxy B12 is a vitamin B12 supplement that combines two active forms of B12 in a single formula. This supplement is often selected by individuals looking to enhance energy metabolism, support nerve function, and promote cellular health. The dual-form approach provides B12 in the specific forms that the body stores in mitochondria and utilises for neurological support, making it a well-rounded choice for maintaining daily vitality.

Key features

• Dual B12 forms: Combines adenosylcobalamin and hydroxycobalamin to support both mitochondrial energy production and neurological health.
• High-potency dose: Each capsule provides 2,000 mcg of vitamin B12, delivering a substantial amount in a single daily serving.
• Mitochondrial support: Adenosylcobalamin is the primary form of B12 stored in mitochondria, supporting the enzyme methylmalonyl-CoA mutase for carbohydrate metabolism.
• Nerve and myelin support: The formula is designed to support healthy synthesis of neuronal myelin, which is essential for proper nerve function.
• Clean formulation: Free from unnecessary additives, artificial colours, sweeteners, and common allergens including wheat, soy, dairy, and eggs.
• Vegan and gluten-free: Suitable for various dietary preferences, with a vegetarian capsule made from cellulose.

What makes Adenosyl/Hydroxy B12 different from standard B12 supplements?

Adenosyl/Hydroxy B12 uses adenosylcobalamin and hydroxycobalamin rather than methylcobalamin alone. Adenosylcobalamin is the form the body preferentially stores in mitochondria, the energy-producing structures within cells, making it particularly suited for supporting cellular energy production. Hydroxycobalamin serves as a precursor to active B12 forms, offering additional support for neurological health.

Is this supplement suitable for vegans?

Yes, Adenosyl/Hydroxy B12 is formulated to be vegan-friendly. The capsule itself is made from plant-based cellulose rather than animal-derived gelatin, and it contains no animal products in its ingredient list.

Can I take this supplement alongside other vitamins or medications?

Whilst B12 supplements are generally well-tolerated, it is advisable to consult a GP or pharmacist before combining Adenosyl/Hydroxy B12 with other supplements or medications, particularly if prescription drugs are being taken or if there are existing health conditions. They can provide guidance on any potential interactions specific to individual circumstances.

How long does it typically take to notice benefits?

The timeframe for noticing benefits varies between individuals and depends on factors such as current B12 levels and overall health status. Some individuals may notice improvements in energy or mental clarity within a few weeks, whilst others may take longer. Consistency with regular use is generally recommended.

Who would benefit most from taking this supplement?

Adenosyl/Hydroxy B12 may be particularly useful for those with limited dietary sources of B12, such as vegans and vegetarians, or those seeking to support energy metabolism and nerve function. It may also appeal to anyone interested in supporting mitochondrial health and cellular energy production.

Are there any ingredients I should be aware of if I have allergies?

Adenosyl/Hydroxy B12 is free from common allergens including wheat, soy, dairy, eggs, tree nuts, peanuts, and sesame. The only other ingredients are hypoallergenic plant fibre and the vegetarian capsule itself. If there are specific allergies or sensitivities, reviewing the full ingredient list is advisable to ensure suitability.