Pure Encapsulations B12 Folate 60 Capsules is a food supplement combining 800mcg of vitamin B12, as methylcobalamin, with 1,333mcg DFE of folate, as Metafolin (L-5-MTHF), in each vegetarian capsule. It's designed for people who want both nutrients together, taken once or twice daily with meals.

Key Features

• Combines methylcobalamin and Metafolin: these are the forms of B12 and folate used in this product, rather than the cyanocobalamin and folic acid found in many standard supplements.
• High-dose B12 (800mcg per capsule): well above the 2.5mcg EU reference intake, in line with typical B12 supplement doses.
• Flexible once or twice daily dosing: 1-2 capsules with meals lets you adjust intake without needing a different product.
• Gluten-free, soy-free and formulated to be hypoallergenic: suits people managing common food sensitivities.
• 60-capsule pack: at 1-2 capsules daily, this provides between one and two months' supply.

What forms of B12 and folate does this contain?

Vitamin B12 is provided as methylcobalamin, and folate as Metafolin (L-5-MTHF). These are different forms from the cyanocobalamin and folic acid used in many standard multivitamins.

Does this interact with any medications?

The manufacturer notes that folate may adversely interact with chemotherapeutic drugs, so anyone undergoing or planning cancer treatment should consult their physician before taking this product. If you're taking any other medication or have a medical condition, check with a healthcare professional first too.

Is B12 Folate suitable for vegetarians?

Yes. The capsule shell is made from plant-based cellulose rather than gelatine, and the formula contains no animal-derived ingredients, gluten or soy.

Why does this provide 800mcg of B12, when the EU reference intake is only 2.5mcg?

800mcg is well above the 2.5mcg EU reference intake, but this is a standard dose for B12 supplements, particularly those using methylcobalamin. If you have questions about whether this dose is right for you, speak to a pharmacist or GP.

Can I take this if I'm pregnant or breastfeeding?

The manufacturer advises that anyone who is pregnant, nursing, taking any medication, has a medical condition, or is planning a medical procedure should consult a healthcare professional before taking this product.

Each vegetarian capsule provides:

Other ingredients: hypoallergenic plant fibre (cellulose), vegetarian capsule (cellulose, water), ascorbyl palmitate.

This product is gluten-free, soy-free, non-GMO and formulated to be hypoallergenic.

Take 1 capsule, 1-2 times daily, with meals.

Do not exceed the recommended dose unless advised by a healthcare professional.

Folate may adversely interact with chemotherapeutic drugs. If you are undergoing or planning cancer treatment, consult your physician before taking this product.

Taking more than 1mg of folic acid a day can mask the symptoms of vitamin B12 deficiency, according to NHS guidance. Each capsule of this product provides more folate than that, alongside a high dose of B12, so it should not be relied on to identify or manage a possible B12 deficiency without a healthcare professional's advice.

If you are pregnant, nursing, have a medical condition, are taking any medication, or are planning a medical procedure, consult a healthcare professional before use.

Food supplements should not be used as a substitute for a varied and balanced diet.

Do not use if the outer seal is damaged or missing. Keep out of reach of children. Store in a cool, dry place.

Vitamin B12 and folate supplements are generally well tolerated at typical doses. High doses of folate can occasionally cause a bitter or unusual taste, loose stools, irritability, difficulty sleeping or stomach cramps. High-dose B12 has been linked to skin reactions such as acne-like breakouts in some people. Stop taking this product and seek medical advice if you experience any persistent or unusual symptoms.